Here's what the blurb says:

The year is nineteen-sixty-something, and after endless millennia of watery sleep, the stars are finally right. Old R'lyeh rises out of the Pacific, ready to cast its damned shadow over the primitive human world. The first to see its peaks: an alcoholic, paranoid, and frightened Jack Kerouac, who had been drinking off a nervous breakdown up in Big Sur. Now Jack must get back on the road to find Neal Cassady, the holy fool whose rambling letters hint of a world brought to its knees in worship of the Elder God Cthulhu. Together with pistol-packin' junkie William S. Burroughs, Jack and Neal make their way across the continent to face down the murderous Lovecraftian cult that has spread its darkness to the heart of the American Dream. But is Neal along for the ride to help save the world, or does he want to destroy it just so that he'll have an ending for his book?

This one is not exactly an easy read - after all, it's been a long time since I read the Kerouac. But how could I resist a description like that? ;)
(Besides, it's been on my wishlist for years. It clearly was high time.)

At first this was really hard to get into - but after I'd read Ginsberg's "Howl" a couple of times, it was much easier going, and I ended up reading the most part of it practically in one go (spending a sunny Sunday inside with a bout of the flu). I really liked it (if that's indeed the right word), especially the solution to the big showdown. So it will spend some more time in my **** Permanent Collection ****.